Bigger is better if you look at the economics of it as you have sandyrusty..
I am draining my FS/Trade list as we are moving soon and do not know if I will return to trading or not once we get settled in or not. The economics of things make buying cards/sets a cheaper option most of the time and doesnt require me to spend hours on end pulling, packing and shipping cards and worrying about postal delays, etc.
I had a recent trade off for a large lot of cards that, once I researched, I could buy the entire set on eBay for less than $10.00 on eBay. So for $10.00, I'm getting the complete set and did not spend time pulling, packing, and mailing cards. Is our time worth something? Most definitely..